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Mesothelioma and Other Asbestos Related Cancers People who have a long exposure to asbestos are at risk of developing a variety of kinds of cancers, including mesothelioma. These diseases have a long latency period, meaning symptoms do not manifest for many years after exposure. The risk of pleural and mesothelioma peritoneal diminishes with time since the first exposure. The evidence is based on six cohort studies of occupational exposure and two residential cohorts that have long-term follow-up. What is Mesothelioma? Mesothelioma or cancer of the inner organs' linings such as the lung (pleural) or abdomen (peritoneal) and heart (pericardial), is a rare and invasive disease. It's a rare and aggressive disease that typically begins in the lining of the chest cavity, but it may also be found in the lining of the stomach or other parts of the body. Asbestos exposure is the primary cause of mesothelioma, and the cancer typically doesn't appear until decades after the initial exposure. People exposed to asbestos in the workplace have a higher risk of developing the disease than other. Asbestos fibres can be swallowed or inhaled and adhere to the organ lining. They can cause irritation to the lining which causes abnormal cells to grow and forming tumors. The symptoms usually don't manifest until a person is diagnosed with advanced mesothelioma. Asbestos exposure most often occurs in jobs in the industrial sector where workers handled the material or worked near it. Asbestos is used in many trades, such as construction, shipbuilding and auto repair. Veterans who served in the military are at a higher danger of mesothelioma since asbestos was extensively used on ships and bases. Anyone with an history of exposure to asbestos should be screened regularly and be aware of any unusual symptoms. If a doctor suspects mesothelioma, they can order imaging scans like CT scans or MRI scans to look for tumors and determine if they've spread. They may also ask about the patient's history of asbestos exposure and perform a physical examination. Certain mesothelioma cases can be linked to genetic changes. So, certain patients could benefit from genetic testing. Risk Factors The exposure to asbestos is the primary mesothelioma-related risk factor. Asbestos is a mineral made of tiny fibers that are strong and resistant to heat. Asbestos is used in many manufacturing and construction products, including insulation, brakes, and shingles. When asbestos is disturbed, it releases dust that could be swallowed or inhaled. This can cause irritation to the mesothelium over time, which can eventually lead to mesothelioma. People who have had a history of occupational asbestos exposure are at greatest risk for mesothelioma. This includes those who worked in industries such as mining, shipbuilding and construction as well as in automotive repair. Military veterans are also at risk since many branches of the military use asbestos-based materials. Other factors that increase the risk of mesothelioma are the family history of asbestos exposure and previous treatment with radiation to the chest. The type of mesothelioma detected has a significant impact on the risk. Pleural mesothelioma, the most common form and typically affects the lungs. Other mesothelioma types include peritoneal, pericardial and testicular. The risk of mesothelioma typically increases with the third or fourth power of latency which is the amount of time it takes to diagnose someone. However, the risk of pleural mesothelioma shows an apparent flattening after about 40 years after exposure. Both peritoneal and pericardial mesothelioma show the same trend. Exposure to asbestos in the workplace like living near an asbestos plant or eating household products that are contaminated, can also increase the risk of mesothelioma. manchester asbestos law firm of six cities showed that those with this type of exposure had a greater mesothelioma risk than those who only had occupational exposure. Signs and symptoms Malignant mesothelioma affects the tissue linings surrounding internal organs. It is most often found in the lining of the lungs (pleura) and abdomen (peritoneum). Mesothelioma may also develop in the tissue of the heart or testicles. It is a rare form of cancer and the majority of people diagnosed with mesothelioma worked in positions that exposed them to asbestos. It could take years for symptoms of mesothelioma to develop, and the disease is not curable. Asbestos is made up of an assortment of minerals that possess microscopic fibers and are resistant to heat, chemicals, and fire. It is widely employed in a variety of industries, such as shipbuilding, construction, manufacturing and more. Exposure to asbestos can cause mesothelioma due to the fibers getting stuck in the tissues that line organs and protect them which causes irritation and damage to cells. This can result in tumors developing and eventually turning cancerous. The most prevalent mesothelioma form is found in the tissue (pleura) of the lungs. It may also begin in the lining of the abdomen (peritoneum) or within the membrane that surrounds the testicles or the heart. Mesothelioma can also spread to the lymph nodes, which causes them to expand. Most people who are diagnosed with mesothelioma are those who have many years of exposure to asbestos, and are suffering from other illnesses like chronic lung disease. The symptoms of mesothelioma are similar to other conditions, so it is important to visit a doctor if you notice any persisting or alarming signs and symptoms. Doctors can inquire about asbestos exposure in the past, and then conduct an examination. They may also conduct scans of your blood and imaging of your chest or abdomen. They can detect any swelling of the lining of your lungs or the fluid that is leaking out of the space between your lungs and chest wall. Diagnosis If asbestos fibers get stuck to the body, they could cause harm and eventually turn into cancerous tumors. Asbestos-related cancers can form in various organs or tissues. Each type of cancer is diagnosed with a different test. Mesothelioma develops in the lining of the chest cavity and the lungs (pleura) and stomach membranes (peritoneum) or around the reproductive organs and the heart. To determine if mesothelioma is a cancer the patient must speak to their doctor about the history of asbestos exposure they have suffered and any signs they are experiencing. Doctors also conduct a physical examination and request basic tests, such as blood work to determine how well the lungs are working. X-rays and CT scans help doctors get a clearer picture of the affected area. In some cases, doctors use a test of pleural fluid to determine if mesothelioma is the cause of the fluid buildup. The pleural effusion may be a symptom of mesothelioma of the pleura, peritoneal mes or a rarer form of mesothelioma called biphasic or mixed mesothelioma. The mesothelioma symptoms are frequently incorrectly diagnosed, since they resemble the symptoms of other diseases. The most common symptoms are breathing difficulties and chest pain. Pleural mesothelioma may also cause chest tightness, cough and fatigue. Peritoneal Mesothelioma could cause abdominal pain, swelling, and distension. Testicular mesothelioma can manifest as a swollen or itchy lump that is located in the testicles. Researchers are studying the proteins in blood to find methods to detect mesothelioma early in its development. They are also researching various other tests and procedures which could improve the accuracy of diagnostics. They are looking at mesothelioma imaging and MRIs. They are also studying genetic mutations, and how to determine if a person is at risk for mesothelioma by taking a look at their family history. Treatment Asbestos exposure is a major mesothelioma-related risk factor. People who have worked with asbestos particularly in high-risk occupations such as construction, electrical work or auto repair, shipbuilding and military service, are at an increased risk. Exposure to asbestos can cause mesothelioma, when fibers become stuck in the tissue that connects vital organs and protects them. The mesothelium is irritated by the asbestos fibers and cause DNA damage that can lead to cancerous cells. Mesothelioma symptoms usually don't manifest until decades after exposure. The symptoms of mesothelioma vary depending on its type and where it is located in the body. The majority of patients with mesothelioma have the lining in their lungs (pleural) but it can also affect the stomach's lining, the heart and testicles. Mesothelioma staging helps doctors determine treatment options. The disease is categorized as stage I through IV with stage I and II being the earliest stages that are the most manageable. Stage III and IV are the more advanced stages of cancer that are more difficult to treat, however there are many treatment options available. Pleural mesothelioma is by far the most common form of the disease that affects the lining of the lungs and chest wall, as well as the abdomen. The majority of cases of pleural mesothelioma are caused by asbestos exposure during work. Most likely, asbestos was inhaled through airborne particles or consumed via food items. Other risk factors include genetic mutation, a family history, and prior treatment for a different disease. If you have been exposed to asbestos and are suffering from mesothelioma symptoms, it is important to see your doctor. You could also benefit from genetic counseling. In some instances mesothelioma experts can help you file a lawsuit against companies who incorrectly use asbestos in everyday products.